S Li was born in Hong Kong and met her husband on May 2, 1985, during a tour trip to Huangshan, China. Their meeting was a fateful encounter, bringing them together despite being thousands of miles apart. After the five-day tour, they parted ways, but their bond grew through letters exchanged over two years. They fell in love and married in August 1987, and S Li moved to the USA to be with her husband. At that time, she was a registered nurse.

With her husband’s encouragement, she pursued her dream of becoming a medical doctor, achieving this goal in 2004. Her husband managed their clinic, allowing S Li to focus solely on medical practice.

In 2019, her husband was diagnosed with acute stage 4 brain cancer, which brought significant changes to their lives. During the last 15 months of his life, he exhibited supernatural behavior, and unexplained events began to occur around S Li after his passing.